Site not loading on WFE2 in SharePoint 2019

Copper Contributor

I have setup a SharePoint 2019 high-availability farm with 2 WFE's, 2 APP and 2 SQL Servers. All servers state is good and patched the farm with May 2022 Cumulative Update. We are running F5 load balancer and public IP of the load balancer (LB) is also added in the host file of both WFE servers.

We created a web application (its public facing site, so also added anonymous authentication) and added DNS to it. We have setup the AAM in central Admin and also added IIS binding for web application port and 443 (wildcard certificate is installed on both WFE servers).

 

When Load Balancer is pointed to WFE1, the application is loading perfectly fine, however when LB is pointed to WFE2, its showing a blank white page (with no JS or CSS loaded on the page, no errors). However, when we do IISRESET on WFE2, first time site loads on WFE2 and then goes blank if we refresh the browser or click on any link on the website. The application is working fine with server name on both the servers.

 

We have tested on different browsers. Also added Disableloopbackcheck in Registry. All required firewall rules (ports) are open. Each server is getting pinged from one another, so there is no server communication issue. Even the required SharePoint files/folders are excluded from antivirus (Bitdefender). Also, there is no other web application on this farm which is using SSL/https.

 

I have also checked SharePoint ULS logs, Event Viewer logs and IIS logs, but it seems there are no errors.

 

Any help would be highly appreciated!

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