Office 365 Upload Center vs One Drive for Business

[Crispin Ali Basah]

I am using both Office 365 and One Drive. Office 365 uploads the file at each save. So does the OneDrive agent that is running in the background. What's the best practice when both features exist? Should I disable Upload Center?

[#2]

Disabling it will also disable co-authoring as detailed here: https://support.office.com/en-gb/article/Use-Office-2016-to-sync-Office-files-that-I-open-8a409b0c-e...