Signature option does not open in outlook 2016

I also faced the same issue I tried this thing and it help. I hope this helps you as well.

I made a backup (Export) of:

HKEY_LOCAL_MACHINE\SOFTWARE\Classes\Wow6432Node\CLSID\{0006F03A-0000-0000-C000-000000000046}\

and then I deleted the key all together. Since then everything has worked fine. Everything in that Key was pointing to an older Office 2013 installation.

Regards,

Lewis

This worked 100% for me .please use this link to fix mutliple scenarios you might face .

Link :  https://www.msoutlook.info/question/899

Proprably your registry singature setting is missing a value all you have to do is to put in the path to outlook.exe loaction . and thats it .please follow the instruction on the link .

The link below is the best solution source for this issue;

https://support.office.com/en-us/article/outlook-freezes-clicking-the-signature-button-c70b36c2-66ca-401c-ab45-f29a46495d02

I tried every solution in here, finaly i tried my fall back:

When in doubt rightclick and run as administrator.

that worked now i can set signature

I have tried all the tricks everyone has mentioned with no success.

I changed the registry entries

I repaired office, both quick and online

I have uninstalled office and reinstalled office 3 times

I deleted all office programs, files and temp files

Still no signature box pops up.

I have tried 32 bit and 64 bit

This is quite ridiculous, brand new computer, brand new install

There was no "Microsoft Office Apps" on the computer prior to installing.

Not sure what to do now. 

When you match the https://medium.com/wikicues/outlook-signature-not-working-outlook-signature-not-opening-7cc722127c4f button, Outlook waves and you are not able to add a signature.

This issue occurs if you install an Office approval on a PC that has pre-installed Microsoft Office desktop apps.

If you uninstall Microsoft Desktop Apps you will no longer have this issue.  Click on start, settings, Apps, Microsoft Desktop Apps and uninstall.  Restart Outlook and you should be able to add a signature.

Hi everyone. Just came across with this issue today. Tried a lot of suggestions in here, but with no success.

Until I tried removing from Windows Registry all keys with the value below:

0006F03A-0000-0000-C000-000000000046

That finally fixed the problem for me. Didn't even need to repair Office installation. 

Thanks for all everyone's posts.

This is what worked for me

1. Open Settings.
2. Click on Apps.
3. Click on Apps & features.
4. Select Microsoft Office Desktop Apps.
5. Click Advanced Options
6. Scroll to the bottom and select Outlook
7. Click Uninstall.
8. Click the Uninstall button to confirm.