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Problem: Excel opened the first file quickly, but the second and subsequent files very slowly
Problem: Excel opened the first file quickly, but the second and subsequent files opened very slowly when launched externally (double click from Explorer or using excel.exe "file.xlsx"). Environmen...
Seems this is well known,learn.microsoft.com/en-au/answers/questions/5223545/excel-opens-2nd-subsequent-file-from-explorer-slow, try restore the ddeexec values under HKEY_CLASSES_ROOT\Excel.Sheet.*\shell\Open\ddeexec