Horizontal Scroll Wheel Useless in Excel?

I'm having a similar issue with the Logitech MX Master 3. For me, the horizontal scroll generally works, however the vertical scroll only works on the first column. If I move the page horizontally at all the vertical scroll no longer works, regardless of if the "scroll lock off" is checked or if I hover over the scroll bar on the right.

I am running the Logitech Options+ software for the mouse.

Any suggestions appreciated!