Conditional Formatting with Multiple Cell Values

Select the Range: Select the range of cells you want to format (e.g., E2:P2). This is the range that will change color based on the conditions.
Create a New Rule: Go to the Home tab, click Conditional Formatting, and then "New Rule".
Use a Formula to Determine Which Cells to Format: Choose this option.
Enter the Formula: This is where the logic for your conditions will go.
For the red condition: =AND(ISNUMBER(E2),H2="F1IL",ISBLANK(J2),ISBLANK(P2))
For the green condition: =AND(ISNUMBER(E2),H2<>"F1IL",ISBLANK(J2),ISNUMBER(P2))
Format the Cells: Click the "Format" button to choose the red fill color for the first condition and green for the second.
Create Another Rule: Repeat steps 2-5 for the green condition.
Order Matters: Ensure the red condition is checked first in the Conditional Formatting Rules Manager (Home -> Conditional Formatting -> Manage Rules). This is important because if both conditions are met, the first one will apply.

AmberTafolla 

Let's say you want to apply this to rows 2 to 100.

Select E2:E100. E2 should be the active cell in the selection.

 

On the Home tab of the ribbon, click Conditional Formatting > New Rule...
Select 'Use a formula to determine which cells to format'.
Enter the formula

=AND($E2<>"", $H2="F1IL", $J2<>"", $P2="")

Click Format...
Activate the Fill tab.
Select red as fill color.
Click OK, then click OK again.

 

Repeat these steps, but with the formula

=AND($E2<>"", $H2<>"F1IL", $J2="", $P2<>"")

and green as fill color.

 

With E2:E50 still selected, double-click the Format Painter button in the Clipboard group of the Home tab of the ribbon.

Click on H2, then on H2 and finally on P2.

Then press Esc to turn Format Painter off.