I am having the same problem with multiple web queries that I have used for years. They have long connection strings that are saved in .iqy files. After I upgraded to Microsoft Office 365 they continued to work for a while but then later started throwing the "Cannot download the information you requested" error. It has completely halted my work. I prefer not to attempt a downgrade back to my old version of Excel. The spreadsheets still work fine on another computer with the older version of Excel. Is there a fix to this issue? Is it a security setting?