Find and replace in all opened documents.

Safe mode starts word with its defaults.

It does not load the Normal.dotm template nor any Add-Ins.

If you write a macro, and save it in the Normal template, when you open in safe mode, you will not have access to it automatically. Both of the linked utilities would be available in safe mode if you loaded them manually as Add-Ins. Neither would be automatically available.

To load a template as an Add-In that is not automatically loaded, you go to the Developer Tab and click on either the Document Template or the Word Add-Ins button and add it. (You do not change the attached template.) When you click on Add, you will get a list of templates that are in the User Templates folder, including the Normal.dotm template. You can move to a different folder.