Using design frameworks for teams

Hi guys,

We are building our web app and want to choose right design frameworks. Our plan is to build a stand alone web application and then to integrate it with Microsoft Teams. As I understand, web applications integrate with Teams using IFrame. 

In the documentation for Teams developers is written that if I want to develop my web app inside Teams (as Teams web app), it is recommended to use Fluent UI Northstar. But if I want to develop just a stand alone web application and then to integrate with Teams, could I use other frameworks like Bootstrap, React bootstrap or Syncfusion? Are there any constraints while integrating with Teams?

Thanks in advance!