Forum Discussion
Unable to "Open in Excel", "Open in Word", etc from SharePoint Online in Chrome
This works for some people, and worked for me in the past. But I am no longer able to: "Open in Word" "Open in PowerPoint" "Open in Excel" Using Office 365 Pro Plus, Deferred Channel, using...
What OS - Windows 10?
Have you tried resetting the default file associations?
Does it work in IE11?
This might not help but there have been instances in the past (as recently as Feb 2016) with people reporting the same behaviour with Chrome https://bugs.chromium.org/p/chromium/issues/detail?id=230316#c16
-Sonia