Is it possible to disable search location in file explorer voa intune

ABill1 This should do all folders in c:\users:

foreach ($folder in Get-ChildItem -Path c:\users -Directory) {
	$folderPath = "C:\Users\$($folder.Name)\appdata\Local\Microsoft\Edge\User Data\Default\Extensions\dlcaglefdlidioooijnigjhfcndlncfp"

	# Define the account for which you want to deny permissions
	$account = "AzureAD\A SPECIFIC USERNAME"

	# Get the current ACL
	$acl = Get-Acl -Path $folderPath

	# Create a rule to deny deletion and deletion of subfolders
	$rule = New-Object System.Security.AccessControl.FileSystemAccessRule($account, "Delete, DeleteSubdirectoriesAndFiles", "Deny")

	# Add the rule to the ACL
	$acl.AddAccessRule($rule)

	# Apply the modified ACL to the folder
	Set-Acl -Path $folderPath -AclObject $acl
}

(No checks if the folder exists and not tested)

But... Like I asked before, a few comments back... Why do you NEED the plugin for secure internet access, and why can people browse the internet without it?! Could they use another browser, too? You have to setup your firewall so the content blocking is done there... That would be better.