Exchange 2013 .net question

Hello!

Quick question... I have a healthy dag (3mbx,2cas) virtual servers. They are running CU21. What it will happen if i will install via windows update .net 4.8? It will destroy the mailbox or the cas servers? I ask this question because i have read somewhere that cu 21 supports .net 4.7.2. Anyone else that already done that?

Thank you