Seeing an issue with edge on the current MacOS Ventura update. Anytime you go to Fullscreen mode on the edge browser, anything in the header you are not able to click on at all. For example, on this site you cannot click on the search or the profile icon at the top of the page. Only limited to edge. Doesn't happen outside of Fullscreen mode though.
Edge version: Version 107.0.1418.42 (Official build) (arm64)