Starting in the last version or two, I frequently get the "spinning wheel of death" after using Remote Desktop for Mac to copy from the remote Windows client. This manifests when I switch back to the mac and try to switch to Slack -- Slack will be frozen for 30 seconds to several minutes with the colorful spinning pinwheel.
Many people have been experiencing this issue, both recently and in the last several years:
Please look into this, it's a productivity killer. And if there's anything I can grab for you that will help (like a snapshot of a process using the Mac activity monitor) please let me know.
EDIT: I just attached a sample and spindump of Slack (the macOS process that gets the spinning wheel of death after copying text on the remote windows machine).