I can't run some .exe files

I have created a customized Win Vista Ultimate installation ISO using vLite. It installs and runs fine.
I have updated the OS with all the WU's.
I created a batch file in the system32 folder and put a shortcut on the desktop which runs fine, so I know that the .bat files work OK.
I can install previous versions of some software, and I can even install some current versions of software. If I double click the .exe file I get the run box, then after clicking run I sometimes get Runtime Error (at -1:0): Cannot import EXPANDCONSTANT [this runs OK on another computer from the same .exe file] OR, nothing happens at all. I can however run the .exe files from an elevated command prompt!