VMM Host Group with existing S2D Cluster

Hello,

I am setting up a Azure Site Recovery and am needing to setup Host Group in VMM, as I don't currently have any, just simply have a cluster with 4 hosts, listed under "All Hosts".  

Can I simply setup a "Host Group" and add the Cluster to it, without affecting on the 12 VMs that are already running on this cluster?

thank you much

Robert

MCWE