Can i enable virtualization based security, system guard and credential guard without impact?

Hi, i think yes but you need to respect requirements for this features at the following link https://learn.microsoft.com/en-us/windows/security/identity-protection/credential-guard/ For Example application guard requires machine reboot, and in my case for new features i apply them of restricted number of device to test that all works fine 🙂 Regards, Guido