Question regarding Exchange 2013 and the /PrepareSchema needed for CVE-2021-34470

Hello experts,

just a quick question here with regards to with regards to Exchange 2013 and the /PrepareSchema needed in addition to application of July 2021 security updates for CVE-2021-34470.

Will it require any downtime of the Exchange Server so that it is advised to run the command during a maintenance window or outside of production hours ?