At Microsoft Ignite, Outlook for iOS and Android announced support for deploying managed device general app configuration settings for Office 365 mailboxes and on-premises mailboxes leveraging hybrid...
Updated Apr 02, 2019
Version 8.0
Blog Post
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New Outlook for iOS and Android App Configuration Policy Experience – General App Configuration
If these devices are MDM enrolled and the native mail profile is managed by the MDM, then yes, you can remove the profile (https://docs.microsoft.com/intune/email-settings-configure#remove-an-email-profile).
If these are not enrolled devices (or the mail profile isn't managed), then there's no admin way of removing it for all devices/clients*. All you can do is block access to EAS and give the users instructions on how to remove the profile manually.
*You could deliver an "account only remote wipe" in Exchange Online, but not all EAS clients support that scenario (some only support a full factory reset type of wipe); see https://support.office.com/article/wipe-a-mobile-device-in-office-365-9d727c7d-8b47-4499-bf24-d046b449214c?ui=en-US&rs=en-US&ad=US