AdamX,
You should not use the same certificate/url for servers in multiple sites. As a general rule, you should consider that you have 1 URL per-site. If you have multiple CAS's in an Internet-facing site, you should load-balance them. If the second site will be Internet-facing (meaning you will have a separate URL entry-point) then you should get a second SSL certificate for the separate URL. If it will be non-internet facing, you will be quite alright to simply leave the default URL's and self-signed certificate in place. Information similar to this is covered in a blog post on my site (http://blogs.msdn.com/brad_hughes/archive/2007/09/10/cas-load-balancing-certificates-autodiscover-and-webservices.aspx)
Hope this helps,
Brad