Andy,
On the profile update tool, here is some more info on what it does and what it does not do; hope that helps:
What this tool will do:
- Delete properties for MAPI_AB_PROVIDER.
- Reset Offline Address Book.
- Deletes the OST if Outlook version is lower than 11 (Outlook 2003).
- Delete Favorites File.
- Deletes maximum receive units (MRU) (relates primarily to delegates).
- Modifies the default profile only. Note: if the client is configured with multiple profiles or set to prompt for the profile to be used, the tool will modify the profile that was last specified as a Default profile.
What it does not do:
- It will not create new profiles and will only modify existing profiles.
- It will not modify profiles other than the default profile (please see the note in the section “What the tool will do” above)
- Will not run on Windows 95 or Windows 98.
Looking overall, if you did a cross-site move, you should either create brand new profiles or should use this tool to fix the default profiles.