Multiple monitors, screen and mouse coordinate system issue

I have multiple monitors with different resolutions. When an RDP connection opens up on one of my screens with fullscreen, and I move it to the other as full screen, (drag and dropping the window to the top bar on the second screen), the mouse is not positioned on the screen correctly any more, and it's not clicking buttons, or clicks somewhere else as I intended. Only after I go out from full screen mode, the RDP resizes and I put it back to full screen again. Then the mouse position is correct, the rdp clicks where it's intended. The connection has Update the session resolution on resize = 1 and Optimize for retina displays = 0.