For those of you who might be interested, we launched Indominus Managed Security in January to address this very problem. We offer a managed instance of Defender for endpoint/for business with 7/24 support and we automated most of the on-boarding. We also optionally offer managed vulnerabilities and updates for Windows devices. We target small and medium businesses who otherwise would not be able to hire/retain cybersecurity professionals. Let me know if we can help.