.Net Core IIS App runs on Server 2016, not on Server 2022

We have an IIS App, a .Net Core application that runs fine on Server 2016. We have .Net framework 4.8 on both servers, IIS 10 on both servers and .Net Core 6.0. What happens on Server 2022 is that we receive an error that says can't reach this page in the browser. We have checked windows firewall rules, event logs, IIS logs and are stuck on this. Any suggestions are appreciated.