IIS app pool in-memory cache miss

Hi,

Our IIS server runs on windows 2016 servers, recently we are experiencing frequent miss from in-memory cache, and instead of connecting to NCache which is our cache solution, it is sending request to database. After lots of debug we still could not identify the issue here. But as a best practice we are going to change some setting. But, one suggestion is to change max worker count from 4 to 1. Will that impact our performance? How much will it be effective to bring that value to 1 from 4, in terms of single worker cache miss issue occurrences?