Forum Discussion
MicrosoftInstall PHPMailer in Azure Web App
Pawel Partyka, as far as I know, Microsoft restricts using smtp on Azure and the best recomendation is to use one of the managed solutions offered by the platform such as send grid. Although if you run a subscription on production, you might find interesting following this doc: https://docs.microsoft.com/en-us/azure/virtual-network/troubleshoot-outbound-smtp-connectivity#recommended-method-of-sending-email
Concerning the application itself, i don't see you having any problems on deploying it.
Just agreeing with carlosdoliveira on this one. I would recommend using the managed SendGrid service. You can send up to 25,000 emails / free / mo. and we've had a lot of success using it. We've also sent using Office 365 SMTP. I personally haven't used PHPMailer, but you're likely going to run into a few roadblocks sending directly through an App Service on the SMTP port(s).