Copy Config Db for Azure DevOps to new server?

I currently am migrating our DevOps server to a new location and I have decided to split the projects into different collections due to size and other reasons.

My question is can I copy the configuration DB, change the URL and more to make this instance unique and have this running while the old DB is running? I primarily don't want to redo our entire server setup while making this as seemless as I can for our users.

Thanks!