Ignite 2025: What's new in Microsoft Defender?

Caroline_Lee

Microsoft

Nov 18, 2025

From advancements in agentic AI to the autonomous SOC of the future, read on to learn about the newest innovations of Microsoft Defender, announced at Ignite 2025.

This Ignite we are focused on giving security teams the edge they need to meet adversaries head on in the era of AI. The modern Security Operations Center (SOC) is undergoing a fundamental transformation, placing AI at the forefront of innovation - not just as an added feature, but as a driving force at every layer of the stack. While much attention is rightly focused on the development of security agents, we fundamentally believe that AI must also evolve the very foundation of our security solutions. This means building solutions that more effectively uncover novel threats, act dynamically to defend the organization during attacks, and reduce the workload for the security team. As organizations adopt AI at an unprecedented speed, we also want to make sure they can do so securely.

To meet these security needs of the AI era, we are excited to announce a series of innovations that will help organizations shift to an autonomous defense and an agentic SOC.

New agents to help scale and accelerate security operations
Evolving Microsoft Defender’s autonomous defense capabilities for better protection
Secure your low-code and pro-code AI agents with Microsoft Defender

Today, we are taking the first step in shifting security operations from static controls to autonomous defense and from manual toil to agentic operations. But we have an ambitious vision to augment and evolve these AI capabilities and agents across the entire SOC lifecycle and are excited to share some of that vision, as shown in the below graphic, with you at Microsoft Ignite.

The Agentic SOC: Scaling expertise and accelerating defense

We are excited to introduce four new Security Copilot agents in Microsoft Defender that bring autonomous intelligence across different stages of the SOC lifecycle. These agents combine context, reasoning, and complex workflows to help defenders anticipate attacks sooner, detect smarter, and investigate faster than ever before.

Phishing Triage Agent: In March 2025, we introduced the Phishing Triage Agent, built to autonomously handle user-submitted phishing reports at scale. The agent reviews and classifies incoming alerts, resolves false positives and escalates only the malicious cases that require human expertise. Early data shows that analysts working with the agent caught up to 6.5x more malicious emails compared to professional graders. Today, we’re excited to announce that the agent’s triage capabilities will soon extend beyond phishing to cover identity and cloud alerts. Secondly, we are also improving our phish admin reporting process with a new agentic email grading system. It replaces a manual review process with advanced large language models and agentic workflows to deliver rapid, transparent verdicts and clear explanations to customers for every reported email. Learn more about the agentic email grading system.
Threat Hunting Agent – this agent reimagines the investigation process. Instead of requiring analysts to master complex query languages or sift through mountains of data, the Threat Hunting Agent enables natural language investigations with contextual insight. Analysts can vibe with the agent by asking questions in plain English, receive direct answers, and be guided through comprehensive hunting sessions. This levels up the current NL2KQL experience by enabling analysts to explore patterns, pivot intuitively and uncover hidden signals in real time for a fluid, context-aware experience. This not only accelerates investigations but makes advanced threat hunting accessible to every member of the SOC, regardless of experience level.
Dynamic Threat Detection Agent – One of the hardest challenges in detection engineering is finding and fixing false negatives. The Dynamic Threat Detection Agent proactively hunts for false negatives and blind spots that traditional alerting might miss. When a critical incident happens, Copilot will kick off an automated hunt to uncover undetected threats—like unusual residual activity around a sensitive identity. This agent turns ‘probably fine’ into proven secure—hunting the quiet persistence that slips past alerts and closing the gap before it becomes tomorrow’s breach.
Threat Intelligence (TI) Briefing Agent – Now native in the Defender portal. Generate tailored, AI‑authored threat briefings in minutes—synthesizing global intel with your environment’s context—without leaving the incident pane.

Figure 1. The Threat Hunting Agent showing insights on an incident that contained a high risk binary

To make the agents easily accessible and help security teams get started more quickly, we are excited to announce that Security Copilot will be available to all Microsoft 365 E5 customers. Rollout starts today for existing Security Copilot customers with Microsoft 365 E5 and will continue in the upcoming months for all Microsoft 365 E5 customers. Customers will receive 30-day advanced notification before activation. Learn more.

Autonomous Defense at Platform Scale

Threat actors are automating everything. Ransomware campaigns can encrypt an entire environment in under an hour. Adversaries evade detection and pivot across identities, endpoints, and cloud resources faster than human teams can triage alerts. Traditional SOC models—built on manual workflows and fragmented tools—simply can’t keep pace. Every second of delay gives attackers an advantage.

Microsoft Defender now counters that speed by delivering autonomous defense at scale. Defender shifts security from reactive firefighting to proactive protection, embedding AI into the foundation of our protection solutions for instant detection, disruption, and containment—before threats escalate. In 2023, we introduced automatic attack disruption, which autonomously stops attacks in progress—like ransomware or business email compromise—with policy-bound actions that isolate endpoints, disable compromised accounts, and block malicious IPs at machine speed.

Today, we’re taking the next step. New capabilities show how AI and agentic technology are transforming security to better protect customers:

Unleash automatic attack disruption across your SIEM data: We are expanding the disruption capabilities of Microsoft Defender to some of the most critical data sources customer connect via Microsoft Sentinel including AWS, Proofpoint and Okta. This enables real-time detection and automatic containment of threats like phishing and identity compromise on top of your log data, fundamentally turning your SIEM into a threat protection solution. While these capabilities leverage the power of our platform, Defender is not a requirement for customers to realize this value in Microsoft Sentinel.

Figure 2. Attack disruption initiated on an AWS attack

Predictive shielding – This brand-new automatic attack disruption capability activates immediately after an attack is first contained. Our first of its kind capability combines graph insights, AI, and threat intelligence to predict potential attack paths for where the adversary might go next. It then applies just-in-time hardening techniques that proactively block the attacker from pivoting. Some of the hardening tactics that will automatically be applied by Microsoft Defender include disabling SafeBoot and enforcing Group Policy Objects, putting a hard stop to the attacker’s movements and ability to execute common techniques for compromise. Learn more about predictive shielding and other endpoint security news.

Protect your low-code and pro-code AI agents

Generative AI and agents are rapidly transforming how we work, but these powerful new tools also introduce new risks. And with the democratization of agent creation across pro-code, low-code, and no-code building platforms, building agents is now accessible to everyone, many without extensive developer or security knowledge.

To help security teams better manage these risks we are excited to announce that we are extending the capabilities and experiences in Microsoft Defender to the protection of agents. From agent security posture management, to attack path analysis, and threat protection for Copilot Studio, Azure Foundry, and agents built and connected via the Microsoft Agent 365 SDK. Learn more about how Microsoft Defender can help protect your agents against threats like prompt injections and more.

There is so much more innovation we are introducing in Microsoft Defender today, including expanded endpoint security coverage for legacy systems, improvements to how you can investigate identity-centric threats, and we are bringing cloud security posture management into the Defender portal. Check out the other Defender news blogs for more details.

Join us in San Francisco, November 17–21, or online, November 18–20, for deep dives and practical labs to help you maximize your Microsoft Defender investments and to get more from the Microsoft capabilities you already use.

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