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Microsoft Defender for Endpoint Blog

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Configuring Microsoft Defender Antivirus for non-persistent VDI machines

Microsoft

Jun 25, 2020

Updated 3/23/2023 to focus on the shared security intelligence feature for VDI. Virtual Desktop Infrastructure (VDI) brings an interesting dynamic when tuning the platform. The delicate balance...

Updated Mar 23, 2023

Version 23.0

Microsoft Defender Antivirus

VDI

JesseEsquivel

Microsoft

Joined April 30, 2020

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baker999855

Copper Contributor

Mar 23, 2021

Also -try adding SYSTEM account permissions - at start-up the machine is querying the folders as the SYSTEM account - so I suspect this might be contributing - although Authenticated Users will also include authenticated computers, perhaps the actual parsing of the definition folders happens under the SYSTEM context -worth bearing in mind!