Case solved !
I added new IP addresses to the network adapter for new websites on the IIS 7 - it seems this has started the problems. I just found a hint on that in this article:
http://social.technet.microsoft.com/Forums/en-US/exchange2010/thread/5f6950b0-7215-479d-9e5e-fb93c76699ce#5f6950b0-7215-479d-9e5e-fb93c76699ce
http://social.technet.microsoft.com/Forums/en-US/exchange2010/thread/5f6950b0-7215-479d-9e5e-fb93c76699ce#5f6950b0-7215-479d-9e5e-fb93c76699ce
After changing the bindung for the Default website in IIS from a specific address (the one which was present at installation of Exchange) to "All unassigned" the Exchange Mangement GUI reacts normal now !
Hope this is useful for others with such problem.