Hi there Exchange team,
I had an install issue where the arbitration mailboxes weren't properly created in an Exchange 2010 multi-domain environment and that stopped the Exchange 2016 CU3 install on the Hub Transport service on the first install (this blog shows the problem well: https://social.technet.microsoft.com/Forums/en-US/af60d888-c1b5-40f2-a5cf-af6038fad5ab/error-during-mailbox-role-transport-service?forum=Exch2016SD)
I could only fix this issue by allowing the Exchange 2010 Schema domain prep to run again by temporarily updating the AD Schema from Exchange 2016 back to Exchange 2010 as that was the only way to properly create the missing/corrupt objects.  So that's issue one that may happen to others.
Then I tried to continue with Exchange install and it kept failing as the installer set all the Exchange services to Disabled at the beginning of the resumed install.  I couldn't uninstall so I simply quickly set all services to automatic once install was restarted again and finally the install completed.
So a couple interest Exchange 2016 clean install issues that may affect others: Fixing arbitration mailboxes on previous Exchange version and then installer issues since Exchange 2016 is partially installed.
-Larry