Released: October 2021 Exchange Server Security Updates

SOLVED:

I solved by following these two articles, the most accurate is that of spiceworks, that of microsoft was not precise on a step, that is, when you create the new certificate, you have to give U, so as not to assign the certificate already, but you have to do it later.
After applying the change, I waited a few hours for it to work, even if you reboot it doesn't change .. it needs a few hours, and now everything is working.

https://community.spiceworks.com/topic/2299094-exchange-2013-on-prem-microsoft-exchange-server-auth-certificate-thumbprint

https://docs.microsoft.com/en-us/exchange/troubleshoot/administration/exchange-oauth-authentication-could-not-find-the-authorization 

thanks to all