Installation of KB5044062 Exchange Server 2019 CU14 Nov24SU failed on 2 servers, see the error below.
After removed Windows Defender Antivirus, and retried the installation, it completed successfully.
MSI (s) (A4:24) [15:26:27:540]: Attempting to delete file C:\Windows\Installer\7fc20.msp
MSI (s) (A4:24) [15:26:27:540]: Unable to delete the file. LastError = 32
MSI (s) (A4:24) [15:26:27:553]: Attempting to delete file C:\Windows\Installer\7fc20.msp
MSI (s) (A4:24) [15:26:27:575]: MainEngineThread is returning 1603
MSI (s) (A4:98) [15:26:27:579]: RESTART MANAGER: Session closed.
MSI (s) (A4:98) [15:26:27:579]: No System Restore sequence number for this installation.
MSI (s) (A4:98) [15:26:27:583]: User policy value 'DisableRollback' is 0
MSI (s) (A4:98) [15:26:27:583]: Machine policy value 'DisableRollback' is 0
MSI (s) (A4:98) [15:26:27:583]: Incrementing counter to disable shutdown. Counter after increment: 0
MSI (s) (A4:98) [15:26:27:583]: Note: 1: 1402 2: HKEY_LOCAL_MACHINE\Software\Microsoft\Windows\CurrentVersion\Installer\Rollback\Scripts 3: 2
MSI (s) (A4:98) [15:26:27:584]: Note: 1: 1402 2: HKEY_LOCAL_MACHINE\Software\Microsoft\Windows\CurrentVersion\Installer\Rollback\Scripts 3: 2
MSI (s) (A4:98) [15:26:27:585]: Decrementing counter to disable shutdown. If counter >= 0, shutdown will be denied. Counter after decrement: -1
MSI (s) (A4:98) [15:26:27:587]: Destroying RemoteAPI object.
MSI (s) (A4:0C) [15:26:27:587]: Custom Action Manager thread ending.
MSI (c) (B8:40) [15:26:27:589]: Back from server. Return value: 1603
MSI (c) (B8:40) [15:26:27:589]: Decrementing counter to disable shutdown. If counter >= 0, shutdown will be denied. Counter after decrement: -1
MSI (c) (B8:40) [15:26:27:589]: PROPERTY CHANGE: Deleting SECONDSEQUENCE property. Its current value is '1'.
Action ended 15:26:27: ExecuteAction. Return value 3.
MSI (c) (B8:40) [15:26:27:589]: Doing action: FatalError
Action 15:26:27: FatalError.
Action start 15:26:27: FatalError.