@Ross-Here is the link to the issue.
http://social.technet.microsoft.com/Forums/en-US/fc26dac5-d4e2-49da-903d-361ea8b85388/451-470-temporary-server-error-please-try-again-later-prx5?Thread%3Afc26dac5-d4e2-49da-903d-361ea8b85388=Microsoft.Forums.Data.Models.Discussion&ThreadViewModel%3Afc26dac5-d4e2-49da-903d-361ea8b85388=Microsoft.Forums.CachedViewModels.ThreadPageViewModel
Steps taken from Premier were to add local server IP to local HOSTS file and to set the Internal and External DNS servers within the Send connectors of the Default Transport and Front-End Transport service all of which are when the Exchange server front
and back-ends reside on the same box. Is this a bug and is it fixed in CU2?