There have been a lot of queries regarding deploying Exchange in a Multi-site/data replication environment. I'll try to answer some of them here.
Deployment Guidelines
The Deployment Guidelines...
Updated Jul 01, 2019
Version 2.0
Blog Post
Good Read!!! Thanks for taking the time to clarify the Microsoft stance on this. I am looking at deploying Synchronous Replication and have dealt with various vendors. Only a couple of which have even brought these considerations to light. Once aware of the issue I was able to work with a vendor who had strong Exchange specific knowledge and references. I urge anyone who is looking at deploying this technology to really do their homework when it comes to failover scenarios, data recovery, and replication performance.