we encountered this the day after installing the patch. when we saw the bulletin from microsoft we uninstalled the rollup straight away
the problem we were having was that it was running out of ram, usually it uses less than 50% of the 18gb installed ram (it's a vm), it was posting messages in the event log that ir was running low on resources and when we looked it was using 94-97% most of
the time, after uninstalling and dealing with the outtage, it went back to normal
i've since installed the re-released patch/rollup on monday night
while it seems to be running ok, it was using 94-96% of the ram again, but no users are having problems as far as i know
i doubled the ram available to this machine last night, thinking that would be overkill, but vmware reports it is using 32gb, and task manager says 28gb ram.