Hi Michael,
- Outlook Mode in E2007 calculator was simply due to the impact Online mode clients could have in terms of IO. In E2010, online mode and cached mode have the same IO profile. However, online mode clients can utilize 3rd party desktop search engines which can impact server IO performance. Thus, the desktop search question.
- Additional IO Requirements / Server adds a total amount of IO for the database host IO requirement. Say you need to ensure that the host supports an additional 400 IOPS on top of the 500 IOPS required by your mailbox population. Therefore you need 900 IOPS. The IOPS Multiplication factor is discussed at http://msexchangeteam.com/archive/2007/07/05/445802.aspx. From your brief description it sounds like you need to break out your Blackberry users into another Tier to use the multiplication factor.
Ross