Timezone setting in ODFB

First you need to set domain admin as the Secondary admin for OD4B. Now you have permission to set timezone for the user. 

Step 1: Script to set Secondary Admin for OD4B

http://www.jijitechnologies.com/blogs/add-remove-secondary-site-collection-admin-to-all-onedrive-for-business-users

Step 2: Now use the below script to set the timezone

# Specify your organization admin central url
$AdminURI = "https://<domianname>-admin.sharepoint.com"
# Specify the User account for an Office 365 global admin in your organization
$AdminAccount = "admin@<domianname>.onmicrosoft.com"
$AdminPass = "pass@word1"
$TimezoneValue= "(UTC+05:30) Chennai, Kolkata, Mumbai, New Delhi"
 
# Specify the secondary admin account and the url for the onedrive site
$siteURI = "https://<domianname>-my.sharepoint.com"
 
$loadInfo1 = [System.Reflection.Assembly]::LoadWithPartialName("Microsoft.SharePoint.Client")
$loadInfo2 = [System.Reflection.Assembly]::LoadWithPartialName("Microsoft.SharePoint.Client.Runtime")
$loadInfo3 = [System.Reflection.Assembly]::LoadWithPartialName("Microsoft.SharePoint.Client.UserProfiles")
 
$sstr = ConvertTo-SecureString -string $AdminPass -AsPlainText -Force
#$AdminPass = ""
$creds = New-Object Microsoft.SharePoint.Client.SharePointOnlineCredentials($AdminAccount, $sstr)
$UserCredential = New-Object System.Management.Automation.PSCredential -argumentlist $AdminAccount, $sstr
 
# Add the path of the User Profile Service to the SPO admin URL, then create a new webservice proxy to access it
$proxyaddr = "$AdminURI/_vti_bin/UserProfileService.asmx?wsdl"
$UserProfileService= New-WebServiceProxy -Uri $proxyaddr -UseDefaultCredential False
$UserProfileService.Credentials = $creds
 
# Set variables for authentication cookies
$strAuthCookie = $creds.GetAuthenticationCookie($AdminURI)
$uri = New-Object System.Uri($AdminURI)
$container = New-Object System.Net.CookieContainer
$container.SetCookies($uri, $strAuthCookie)
$UserProfileService.CookieContainer = $container
 
# Sets the first User profile, at index -1
$UserProfileResult = $UserProfileService.GetUserProfileByIndex(-1)
Write-Host "Starting- This could take a while."
$NumProfiles = $UserProfileService.GetUserProfileCount()
$i = 1
 
Connect-SPOService -Url $AdminURI -Credential $UserCredential
 
# As long as the next User profile is NOT the one we started with (at -1)...
While ($UserProfileResult.NextValue -ne -1)
{
Write-Host "Examining profile $i of $NumProfiles"
# Look for the Personal Space object in the User Profile and retrieve it
# (PersonalSpace is the name of the path to a user's OneDrive for Business site. Users who have not yet created a 
# OneDrive for Business site might not have this property set.)
$Prop = $UserProfileResult.UserProfile | Where-Object { $_.Name -eq "PersonalSpace" }
$Url= $Prop.Values[0].Value
 
# If OneDrive is activated for the user, then set the secondary admin
if ($Url) {
$sitename = $siteURI + $Url
$Site = $sitename
$Context = New-Object Microsoft.SharePoint.Client.ClientContext($Site)
$Context.Credentials = $Creds
$TimeZones = $Context.Web.RegionalSettings.TimeZones
$Context.Load($TimeZones)
$Context.ExecuteQuery()
$RegionalSettings = $Context.Web.RegionalSettings
$Context.Load($RegionalSettings)
$Context.ExecuteQuery()
$TimeZone = $TimeZones | Where {$_.Description -eq $TimezoneValue}
$RegionalSettings.TimeZone = $TimeZone
$Context.Web.Update()
$Context.ExecuteQuery()
Write-Host "Time Zone successfully updated for $($site) "
 
}
 
# And now we check the next profile the same way...
$UserProfileResult = $UserProfileService.GetUserProfileByIndex($UserProfileResult.NextValue)
$i++
}