DFS REPLICATION & DATA DEDUPLICATION

[HWLUSER]

According to this article...

https://docs.microsoft.com/en-us/windows-server/storage/data-deduplication/interop

If using dedup with Storage Replica...Data Deduplication should be configured to not run on the secondary copy.

It does not say this when using DFS REPLICATION.  The question is should I run dedup on both or just the primary?

[#2]

@HWLUSER 

Depending your scenario, you could enable dedup on one or both the source or target.
You could run ddpeval on your dataset to check if there is a benefit from enabling deduplication.

You might want to look at Azure Files vs DFS.  Azure File Sync with multiple endpoints with cloud tiering, deduping only locally cached files. 

It can be configured right from Windows Admin Center.