Win 10 Pro clone of my C-drive no longer boots from USB

Occasional Visitor

11/23/20 – Strange problem that I’m thinking is Windows oriented

 

Something I’ve always done over the years is run weekly 100% mirror image bootable backup clones of the C-drive in my ThinkPad laptops…using spare USB cable connected SSD hard drives.  [ connect the drive, run ‘Acronis True Image’ cloning software that I use, done ]
From time to time I’d boot the laptop from a USB backup drive, always worked perfectly…but mostly I’d just make the weekly backups for peace of mind in case the C-drive should ever fail.

 

But discovered a pesky little problem as I’ve been setting up a new ThinkPad P52 to replace my older P51.  After I finished setting up the new P52 C-drive, I cloned it to a USB attached hard drive like I’ve done on the P51 a couple hundred times…and then just to be sure it worked, tried to boot the P52 back from the cloned USB attached drive.
Failed…blue screen error message: “Inaccessible Boot Device”.

 

TROUBLE SHOOTING SUMMARY SO FAR:

The P52 ThinkPad boots up normally / works perfectly from its internal C-drive.

All USB flash drives and/or USB cabled hard drives that I plug in all operate normally.
The P52 laptop sees them all, adds them to the list of other drives in the laptop (c, d, e, f, etc.).

I can read/ write to them business as usual, click open / look at content inside normally.

My cloning software works like always because I’ve taken cloned copies and physically installed them inside the laptop as the internal C-drive and the laptop comes right up normally / works perfectly, etc.  I simply cannot BOOT FROM a USB connected clone any longer.

 

I’ve spent hours over a few days Internet searching, trying this, trying that, no help.
I’ve tried different SSD hard drives, different cables, different USB ports, no help.

Ran a few check-disk kinds of scans and the SSD’s are rock solid as always.

Ensured all Lenovo ThinkPad updates are downloaded and installed.
Ensured all Windows updates are downloaded and installed.

Then started trying the approach of uninstalling Windows updates one at a time but it’s time consuming and several of the ‘security related Win updates wouldn’t let me uninstall them.

  

So I decided to go back and ensure everything sill worked OK on the original P51, and to my surprise it fails the same way.  Been quite a while since I actually did a USB Boot on the original P51 so I assume something must have changed during the past several months and I’m thinking the Win 10 Pro software is the common denominator.

Thought I’d check here with the Community Forum Brain Trust and see if anyone might know of a specific Win 10 related finding / fix for this situation…thanks a lot in advance.

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