Jan 31 2022
It's been a while since I worked actively with sharepoint designs.I remind from the past that it was possible to create organization wide lists.Besides site specific lists.
May 10 2022
i'm not sure, what you mean with org-wide lists. Is it possible, hat you mean the term store? With the tenant term store you can manage metadata, it's a central store for values and you can use this values org-wide.
See more: https://docs.microsoft.com/en-us/sharepoint/create-and-manage-terms