SAP S/4HANA choose best IaaS

[RaadAlrawi]

Hello Folks 

I need some help and advice from you, I have this requirement below and I need to know what is the best to choose:

Type	System usage	Usage	CPU SAPS	RAM in GB	SAP needed Storage
S/4HANA-APP	S4H-DEV	DEV	8000	16	200 GB
S/4HANA-APP	S4H-QAS	QAS	8000	24	200 GB
S/4HANA-APP	S4H-PRD	PRD	6000	16	200 GB
S/4HANA-APP	S4H-PRD	PRD	16000	64	200 GB
S/4HANA-DB	HANA-DEV	DEV	HANA certified appliance of 256 GB of RAM or equivalent  certified TDI
S/4HANA-DB	HANA-QAS	QAS	HANA certified appliance of 384 GB of RAM or equivalent  certified TDI
S/4HANA-DB	HANA-PRD	PRD	HANA certified appliance of  512 GB of RAM or equivalent  Certified TDI
PO/Sybase	PO-DEV	DEV	8000	16	256 GB
PO/Sybase	PO-QAS	QAS	12000	32	512 GB
PO/Sybase	PO-PRD	PRD	16000	64	1 TB
Services	SAP-router	PRD	4000	8	20 GB
Services	SolMan	PRD	8000	24	800 GB
Services	ADS-PRD	PRD	6000	16	500 GB
Services	Jump-box	PRD	6000	16	2TB
			114 Core	1,392 GiB	3.6 Tera

first I go to SAP and check the hardware certified and TDI then I select Azure IaaS platform it is about 118 and selects one of them:  ( M128ds_v2 ) this one I think feel it is fit to me, so this one gives me one virtual machine or I can run all VMs Above 

Thank you in advance 

[#2]

Hi RaadAlrawi
I believe it should be M series for sure to give you a better flexibility for cache:
For standard storage, the possible cache types are:
None
Read
Read/Write
To get consistent and deterministic performance, set the caching on standard storage for all disks that contain DBMS-related data files, log and redo files, and tablespace to NONE. The caching of the base VHD can remain with the default.

For Azure premium storage, the following caching options exist:
None
Read
Read/write
None + Write Accelerator, which is only for Azure M-Series VMs
Read + Write Accelerator, which is only for Azure M-Series VMs
For premium storage, we recommend that you use Read caching for data files of the SAP database and choose No caching for the disks of log file(s).
For M-Series deployments, we recommend that you use Azure Write Accelerator for your DBMS deployment.
Reference:
https://learn.microsoft.com/en-us/azure/virtual-machines/workloads/sap/dbms_guide_general
The general guidance is to use an average target CPU utilization of 65%. If your average utilization is below 30%, the CPU is considered oversized.
In particular, SAP Note #1872170 documents reports (/SDF/HDB_SIZING and ZNEWHDB_SIZE) that facilitate estimating the memory and disk space requirements for the database tables of Business Suite on HANA, S/4HANA
Thanks,