When Cisco AnyConnect is open and disconnected, I am not having any issues. Once I establish a VPN connection with it to a client site, the File Explorer on my local machine becomes unresponsive. I have tried multiple different things and only experience this issue when connected with Cisco AnyConnect. I am still able to connect to remote server using Microsoft Remote Desktop without any issue, but when I try to access drives on my local machine, File Explorer hangs.
I am running a Ryzen 5800x processor with 32 GB of ram. I checked resources and they are perfectly fine. I even rebooted a couple times in testing this.