Bookmarks are usually for a specific link, tool or site. Topics and Microsoft Search work well together already. If there's a topic card available for a topic as a high confidence result at the top of the page, it will appear in the search results. If you have a bookmark, that will supersede the topic card if there's both a bookmark and a topic with exactly the same name.
Will this also be the same for acronyms? the topic card will include the acronym (if I am right), so I would want to have the topic card show in search for the acronym and not my acronym list that I currently have. (FYI, we are only piloting topics right now and have not fully rolled it out)
I created one topic on my own to see what it would do but haven't done much past editing the AI suggested ones. It has been a lower priority for us until now. We are going to really start working on it this summer. But with over 3000 AI suggested topics, I think I am mainly going to be editing. :)