Microsoft Defender Antivirus Error Code -2016281112

[John Matrix]

Hello community,

we have a lot of Windows 10 devices where one setting of the Defender Antivirus Configuration (deployed via Intune) has the status error.

We have no third party AV solution active on these devices.

Any ideas how I can find the origin of this error?

Defender Security Intelligence Update also fails on these devices:

Thanks.

-John

[#2]

@John Matrix Did you check the event viewer for the affected device to see if there are helpful pointers?

1. Open Event Viewer.
2. In the console tree, expand Applications and Services Logs, then Microsoft, then Windows, then Windows Defender.
3. Double-click on Operational.