Server (2008 R2) already has all of the most recent pages or at least to the published date of this article. Exchange is up to Rollup 21. .NET frame is up to 2018-05 Security Rollup (KB4099633) Server Windows 2008 R2 is at 2018-06. Attempted to install the TLS .net update and does not apply, probably as the installed version is newer than this patch.
I did find the registry keys and enabled TLS 1.2 (enabled:1) and applying the Rollup 22 now.