I have a requirement for SCL's to be set on a per mailbox basis. You can do this on premises using the Set-Mailbox cmdlet with applicable setting e.g.
Set-Mailbox -Identity bobsmith -SCLDeleteThreshold 3
The TechNet artcile says these options are not available in Exchange Online. Has anybody else had this requirement and if so, what have you done to achieve it?
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Best you can do is create several Spam filter policies and apply them to different users as needed. Details are here: https://technet.microsoft.com/en-us/library/jj200684(v=exchg.150).aspx