Ross Smith IV writes the authoritative guide on the preferred Architecture for Exchange 2016.
https://blogs.technet.microsoft.com/exchange/2015/10/12/the-exchange-2016-preferred-architecture/Try to build your 2016 environment as closely to the PA as possible. I have built several Exchange 2016 environments for customers following this guide and it has worked out very well for me and my clients.
Next, download a copy of the Role Requirements Calculator, as this will help you size the disks properly:
https://gallery.technet.microsoft.com/Exchange-2013-Server-Role-f8a61780Then, when you are ready to do the install, follow the Deployment Assistant wizard here:
https://technet.microsoft.com/en-us/office/dn756393.aspxThere is some new Exchange 2016 training that just became available that you might want to look at.
https://blogs.office.com/2016/05/17/exchange-server-2016-online-training-courses-now-available/Also, just curious, have you considered migrating to Exchange Online to avoid the cost of building and supporting this on-premises environment?