In the latest Edge Canary browser, Version 81.0.411.0 (Official build) canary (64-bit),
there is this new option added in the Settings:
You can set your default profile and also open links on the web in different profiles from the right-click menu.
as you can see I have 2 profiles on my Edge canary right now (1 is connected to my Outlook.com and the other is an offline/local profile).
my Outlook.com profile is set as default, but now I have the ability to open links on my 2nd profile too.