Microsoft Remote Desktop has a memory leak. This started a few versions back; I thought maybe it would be fixed in succeeding versions, but it has not. You can watch with Task Manager and see it slowly consume more memory. It starts out with about a 50MB footprint, but I've seen it at over 4GB before I had to kill it. Right-clicking on the icon in the system tray did nothing (unresponsive). So there is an issue somewhere. I'm not sure what triggers the increase in memory utilization, as it seems to be stable at first.
Edition Windows 10 Pro Version 22H2
OS build 19045.4717
Experience Windows Feature Experience Pack 1000.19060.1000.0